Metabolic Health Protocols

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Integrative supplement protocols to support metabolic health — curated by Dr. Kendra using evidence-based research and professional-grade ingredients.

All supplements available through Dr. Kendra's Fullscript Dispensary with a 10% patient discount.

Weight & Metabolic Support

When your metabolism isn't working efficiently, it can show up as stubborn weight, energy crashes after meals, or blood sugar swings that leave you reaching for snacks you don't really need. These supplements work at the cellular level to help your body process sugar and fat more effectively — think of them as tools that help your engine run cleaner.

  • Berberine 500mg (Integrative Therapeutics, ~$30) — This plant compound works similarly to metformin, one of the most commonly prescribed blood sugar medications. It activates an enzyme called AMPK — your cells' "energy sensor" — which helps your body burn glucose and fat more efficiently. Research shows it can lower fasting blood sugar and support healthy body composition.
  • Green Tea Extract (EGCG) (Pure Encapsulations, ~$30) — EGCG is the active compound in green tea that supports metabolism. It gently increases your metabolic rate and helps your body break down fat, especially when combined with moderate exercise. It also has powerful antioxidant properties that protect your cells from damage.
  • Magnesium Glycinate (Pure Encapsulations, ~$25) — Magnesium plays a role in over 300 enzyme reactions in your body, including how you process sugar and produce energy. Many people are deficient without knowing it. The glycinate form is gentle on the stomach and well-absorbed. Dr. Kendra recommends this form specifically because it's less likely to cause digestive upset.
  • ProOmega 2000 (Nordic Naturals, ~$49) — High-concentration omega-3 fatty acids (EPA and DHA) that reduce inflammation throughout your body. Chronic low-grade inflammation is a major driver of metabolic problems. These healthy fats also support heart health and help your body respond better to insulin.
  • Vitamin D3 5,000 IU (Pure Encapsulations, ~$15) — Vitamin D deficiency is extremely common and linked to insulin resistance, weight gain, and metabolic syndrome. This dose helps bring levels into the optimal range. Dr. Kendra recommends checking your levels with a blood test so dosing can be personalized.

Estimated monthly cost: ~$150 (before your 10% Fullscript discount)

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Blood Pressure Support

High blood pressure often has no obvious symptoms, which is why it's called the "silent killer." While medication is sometimes necessary, these supplements can support healthy blood pressure alongside lifestyle changes like reducing sodium, managing stress, and staying active. They work through different mechanisms — relaxing blood vessels, supporting heart muscle function, and helping your body maintain healthy fluid balance.

  • Magnesium Glycinate (Pure Encapsulations, ~$25) — Magnesium helps relax blood vessel walls, which naturally lowers pressure. Studies show that people with low magnesium levels tend to have higher blood pressure. This is one of the most important supplements for cardiovascular health overall.
  • Ubiquinol-QH 100mg (Pure Encapsulations, ~$50) — This is the active, ready-to-use form of CoQ10. Your heart is one of the most energy-demanding organs in your body, and CoQ10 is essential for cellular energy production. Research shows it can reduce both systolic and diastolic blood pressure over time.
  • ProOmega 2000 (Nordic Naturals, ~$49) — Omega-3s reduce inflammation in blood vessel walls and help prevent the stiffness that drives blood pressure up. Multiple clinical trials show meaningful blood pressure reductions with high-dose fish oil.
  • Aged Garlic Extract (Kyolic/Wakunaga, ~$30) — Aged garlic extract has been studied extensively for blood pressure. The aging process creates unique sulfur compounds that help blood vessels relax and dilate. It's odorless and gentle on the stomach, unlike raw garlic supplements.
  • Potassium Citrate (Pure Encapsulations, ~$20) — Potassium counterbalances sodium in your body. Most Americans get far too much sodium and not enough potassium. This supplement helps restore that balance, supporting healthy blood pressure. See important safety note below before taking potassium.

⚠️ Important — Potassium Safety Warning: Do NOT take potassium supplements without consulting your doctor if you have kidney disease, are taking ACE inhibitors (lisinopril, enalapril, ramipril), ARBs (losartan, valsartan, irbesartan), or potassium-sparing diuretics (spironolactone, amiloride, triamterene). These medications can raise potassium levels, and adding a supplement on top may cause dangerously high potassium (hyperkalemia), which can lead to serious heart rhythm problems. Your doctor can check your potassium levels with a simple blood test before you start.

Estimated monthly cost: ~$174 (before your 10% Fullscript discount)

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Cholesterol Support

Cholesterol isn't inherently bad — your body needs it to build cells and make hormones. The problem arises when LDL ("bad" cholesterol) gets too high or becomes oxidized, leading to plaque buildup in your arteries. These supplements target cholesterol through multiple pathways: reducing production, blocking absorption, and helping your body clear it more efficiently.

  • ProOmega 2000 (Nordic Naturals, ~$49) — High-dose omega-3s are especially effective at lowering triglycerides (blood fats) and can improve your overall cholesterol profile. The EPA in fish oil also helps prevent cholesterol from oxidizing, which is when it becomes truly dangerous to your arteries.
  • Red Yeast Rice + CoQ10 (Thorne, ~$42) — Red yeast rice naturally contains monacolin K, which works like a mild statin to reduce cholesterol production in your liver. The added CoQ10 is important because — just like prescription statins — red yeast rice can lower your body's CoQ10 levels. This combination gives you the benefit with built-in protection.
  • Berberine 500mg (Integrative Therapeutics, ~$30) — Beyond blood sugar, berberine also helps lower LDL cholesterol and triglycerides. It works through a different pathway than red yeast rice, so they complement each other well. Think of it as a metabolic multi-tasker.
  • Foresterol 600mg (Plant Sterols) (Designs for Health, ~$46) — Plant sterols look similar to cholesterol at the molecular level, so they compete with cholesterol for absorption in your gut. This means less dietary cholesterol gets into your bloodstream. Studies consistently show a 5–15% reduction in LDL with regular use.
  • Organic Whole Husk Psyllium (Organic India, ~$18) — Soluble fiber acts like a sponge in your digestive tract, binding to bile acids (which are made from cholesterol) and carrying them out of your body. Your liver then has to pull more cholesterol from your blood to make new bile acids, naturally lowering your levels.

Estimated monthly cost: ~$185 (before your 10% Fullscript discount)

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Blood Sugar & Insulin Resistance Support

When your body stops responding efficiently to insulin — a condition called insulin resistance — sugar builds up in your blood instead of getting into your cells where it's needed for energy. Over time, this can lead to type 2 diabetes, weight gain, and fatigue. These supplements help your cells become more sensitive to insulin again and support healthy blood sugar regulation.

  • Berberine 500mg (Integrative Therapeutics, ~$30) — Dr. Kendra's top recommendation for blood sugar support. Berberine activates AMPK, the same pathway that metformin targets, helping your cells take in glucose more effectively. Multiple clinical trials show it can lower HbA1c (your 3-month blood sugar average) as effectively as some prescription medications.
  • Chromium Picolinate 500mcg (Pure Encapsulations, ~$18) — Chromium is a trace mineral that enhances insulin's ability to do its job. Think of insulin as a key and your cell as a lock — chromium helps the key turn more smoothly. It's especially helpful if you experience sugar cravings, which can be a sign of chromium deficiency.
  • Alpha Lipoic Acid 600mg (Pure Encapsulations, ~$61) — This powerful antioxidant works in both water and fat (most antioxidants only work in one), giving it unique protective abilities. It improves insulin sensitivity and helps protect your nerves from high-sugar damage — which is why it's also in the neuropathy protocol.
  • ProOmega 2000 (Nordic Naturals, ~$49) — Omega-3s reduce the chronic inflammation that worsens insulin resistance. They also help protect your cardiovascular system, which is especially important because blood sugar problems and heart disease often go hand in hand.
  • Magnesium Glycinate (Pure Encapsulations, ~$25) — Low magnesium is strongly associated with insulin resistance and type 2 diabetes. Supplementing helps your body process glucose and can reduce fasting blood sugar levels. Many diabetes medications actually deplete magnesium, creating a vicious cycle that supplementation can break.

Estimated monthly cost: ~$183 (before your 10% Fullscript discount)

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→ Browse All Metabolic Health Supplements on Fullscript

Important: These supplements are meant to support — not replace — the care you receive from your doctors and specialists. Always talk to your healthcare provider before starting any new supplement, especially if you take prescription medications. Supplements can interact with medications including blood thinners, blood pressure drugs, and diabetes medications.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.